02-P005 A mechanism for “brain sparing” during dietary restriction in Drosophila
نویسندگان
چکیده
منابع مشابه
02-P005 A mechanism for “brain sparing” during dietary restriction in Drosophila
phology. We have generated a Tg(phd3:GFP)/+; vhl1/+ transgenic line, which exhibit robust GFP expression in the vhl1/vhl1 background, essentially acting as an in vivo fluorescent reporter to identify the mutant cells/embryos. To induce VHL kidney tumors in fish, we have utilized this transgenic line to generate donor embryos and transplanted the mutant blastomeres to the wild type host embryos,...
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While the growth of the developing brain is known to be well-protected compared to other organs in the face of nutrient restriction (NR), careful analysis has revealed a range of structural alterations and long-term neurological defects. Yet, despite intensive studies, little is known about the basic principles that govern brain development under nutrient deprivation. For over 20 years, Drosoph...
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ژورنال
عنوان ژورنال: Mechanisms of Development
سال: 2009
ISSN: 0925-4773
DOI: 10.1016/j.mod.2009.06.035